PO-02-140 CENTRAL RETINAL ARTERY OCCLUSION: A SYSTEMATIC REVIEW AND META-ANALYSIS FOR THE RISK OF NEW-ONSET ATRIAL FIBRILLATION AND STROKE

Central retinal artery occlusion (CRAO) is a devastating event and atrial fibrillation (AF) recognized cause that may not be present at the time of event. We aimed to estimate association CRAO with risk new-onset AF stroke during follow-up by performing systematic review meta-analysis published data. searched databases MEDLINE, Embase SCOPUS from inception May 2022 for terms ‘atrial fibrillation’ ‘retinal occlusion’ identified 205 studies. excluded duplicates, non-relevant studies those reporting after CRAO. used random effects models calculate pooled odds ratio (OR) 95% confidence intervals (CI) in patients or comparison control groups. Analysis was performed RevMan 5.4.1 (Cochrane 2020). included 7 1.476 compared group without (n=9.843) (n=7.058). There were 196 new cases (13.4%) 18 months associated higher (OR:1.59, CI:1.20-2.11, p=0.001) (OR:2.46, CI:1.74-3.47, p<0.001) when controls. However, similar (OR:0.83, CI:0.41-1.71, p=0.62). stroke. though Thus, should regarded as cryptogenic mandate closer screening evaluation early anticoagulation.